Web Reference: Clustal Omega is a new multiple sequence alignment program that uses seeded guide trees and HMM profile-profile techniques to generate alignments between three or more sequences. What is a multiple sequence alignment? A multiple sequence alignment is simply an alignment of more than two sequences, like this: (A small section of six tyrosine kinase protein sequences.) Definition: Given k strings, S1, S2, ... , Sk, a multiple sequence alignment (MSA) is obtained by inserting gaps in the strings to make them all the same length.
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