Web Reference: Codeine / promethazine syrup is usually used to make lean, but other syrups are also used. Users of lean are at risk of addiction, and serious complications include respiratory depression, respiratory arrest, and cardiac arrest. Lean is especially dangerous when consumed with alcohol. Jan 10, 2025 · Drinking Lean is not safe. The combination of codeine, promethazine, and other ingredients can cause serious health risks, including respiratory depression, organ damage, and addiction. Lean, or purple drank, is a mixture of prescription cough syrup with codeine and promethazine, soda, and candy. It has sedative effects and can be dangerous.
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