Web Reference: Jul 7, 2022 · Katherine revealed to Bonnie at the last moment that if she couldn’t have Stefan, than no one could, especially not Elena. So, before she died, she injected herself with Dr. Wes’ needle — which means that now, Elena will be feeding off of vamps, too. Because Katherine was no longer human, her blood no longer was a viable component of the ritual to undo the curse. Klaus was so infuriated with Katherine's sabotage, that she was forced to live on the run for over 500 years as he hunted her down. If the cure was taken out and it stopped her from being a vampire, she should have just gone back to being a vampire or stayed human because it’s a permanent change.
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